Journal Article

Effects of consistent atrial pacing and atrial rate stabilization - two pacing algorithms to suppress recurrent paroxysmal atrial fibrillation in brady-tachy syndrome

G. Boriani, M. Biffi, L. Padeletti, A. Sparnpinato, G. Luca Botto, C. Pignalberi, A. Grammatico, D.A. Hettrick, F. De Seta and A. Branzi

in European Heart Journal Supplements

Published on behalf of European Society of Cardiology

Volume 3, issue suppl_P, pages P7-P15
Published in print November 2001 | ISSN: 1520-765X
Published online November 2001 | e-ISSN: 1554-2815 | DOI: http://dx.doi.org/10.1016/S1520-765X(01)90067-7
Effects of consistent atrial pacing and atrial rate stabilization - two pacing algorithms to suppress recurrent paroxysmal atrial fibrillation in brady-tachy syndrome

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Background and method Recently, various dedicated atrial pacing algorithms have been proposed to prevent atrial fibrillation (AF). Consistent atrial pacing (CAP; an algorithm for automatic atrial overdrive) and atrial rate stabilization (ARS; an algorithm for preventing the ‘short-long’ sequences) were tested in 16 patients with brady-tachy syndrome and recurrent paroxysmal AF (≥3 episodes per month).

Results In the population as a whole, pacing with CAP was associated with a significant reduction in AF burden in comparison with DDDR pacing. With regard to the effects on AF burden, 11 patients (69%) were found to benefit significantly from CAP or ARS pacing algorithms (reduction >50% in AF burden). In detail, seven patients were responders to both algorithms, two to CAP only and two to ARS only. Two patients exhibited a significant increase in AF burden with the ARS algorithm. With regard to the effects on number of mode switches per day, seven patients (44%) were found to benefit significantly from CAP or ARS pacing algorithms (reduction in mode switches per day >50%). In detail, five patients were responders to both algorithms and two to ARS only. Two patients had a significant increase in the number of mode switches per day with both CAP and ARS algorithms.

Conclusion The response to ARS and CAP algorithms is heterogeneous. In 31–69% of patients with brady-tachy syndrome a significant reduction in AF burden and/or mode switch episodes can be obtained with ARS and/or CAP algorithms; however, in a few patients an increase in AF episodes and/or AF burden may occur

Keywords: Atrial fibrillation; brady-tachy syndrome; dual-chamber pacing; pacing algorithms; overdrive atrial pacing; rate responsive

Journal Article.  0 words. 

Subjects: Cardiovascular Medicine

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