Journal Article

Dementia at old age: a clinical end-point of atherosclerotic disease

G.J. Blauw, E.L.E.M. Bollen, M.A. van Buchem and R.G.J. Westendorp

in European Heart Journal Supplements

Published on behalf of European Society of Cardiology

Volume 3, issue suppl_N, pages N16-N19
Published in print November 2001 | ISSN: 1520-765X
Published online November 2001 | e-ISSN: 1554-2815 | DOI: http://dx.doi.org/10.1016/S1520-765X(01)90133-6
Dementia at old age: a clinical end-point of atherosclerotic disease

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The main causes of dementia at old age are Alzheimer's disease and vascular dementia. The clinical presentations of late-onset Alzheimer's disease and vascular dementia can barely be differentiated. This clinical observation is supported by pathological findings. Late-onset dementia should be considered a multifactorial disease, in which both vascular factors and amyloid dispositions contribute to cognitive decline.

Keywords: Alzheimer's disease; atherosclerosis; 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins); pravastatin; vascular dementia

Journal Article.  0 words. 

Subjects: Cardiovascular Medicine

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