Journal Article

The evaluation of right ventricular performance in different clinical models of heart failure

Carlo Campana, Michele Pasotti, Lorenzo Monti, Miriam Revera, Alessandra Serio, Luisa Nespoli, Giulia Magrini, Laura Scelsi, Stefano Ghio and Luigi Tavazzi

in European Heart Journal Supplements

Published on behalf of European Society of Cardiology

Volume 6, issue suppl_F, pages F61-F67
Published in print November 2004 | ISSN: 1520-765X
Published online November 2004 | e-ISSN: 1554-2815 | DOI: http://dx.doi.org/10.1016/j.ehjsup.2004.09.012
The evaluation of right ventricular performance in different clinical models of heart failure

Show Summary Details

Preview

Aim

To evaluate the role of right ventricular function in different clinical models of heart failure.

Methods

22 patients with pulmonary hypertension (PH) in WHO class III and IV (group A) were evaluated by echocardiography, brain natriuretic peptide (BNP) measurements and right heart catheterization at baseline and after a mean follow-up of 15±4 months. 63 patients with chronic heart failure of different etiology, NYHA class IIIb–IV, followed-up for 18±3 months (group B), underwent echocardiography, BNP measurements, right heart catheterization at study entry and follow-up.

Results

In group A patients, among hemodynamic parameters consistent with severe PH, right atrial pressure significantly increased (from 6.7±4.8 to 10±6.5 mmHg, p<0.01); BNP showed a negative correlation with right ventricular ejection fraction (r2=0.46). In group B, mean left and right ventricular (thermodilution) ejection fraction (RVEF) were 21±7% and 18±9%; BNP showed significant correlations with pulmonary wedge pressure (r=0.48, p=0.02) and right ventricular function indices (RVEF and tricuspidal annular plane systolic excursion).

Conclusions

A multiparametric right ventricular evaluation is useful even if several diagnostic and prognostic variables which were investigated in this study are not likely to show the same prognostic role in right and biventricular models of heart failure.

Journal Article.  4054 words.  Illustrated.

Subjects: Cardiovascular Medicine

Full text: subscription required

How to subscribe Recommend to my Librarian

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.