Journal Article

Obesity, weight loss and heart failure

Rita Mariotti, Francesca Castrogiovanni, Francesco Becherini, Bernardo Cortese, Lorenzo Rondinini and Mario Mariani

in European Heart Journal Supplements

Published on behalf of European Society of Cardiology

Volume 6, issue suppl_F, pages F87-F90
Published in print November 2004 | ISSN: 1520-765X
Published online November 2004 | e-ISSN: 1554-2815 | DOI: http://dx.doi.org/10.1016/j.ehjsup.2004.09.013
Obesity, weight loss and heart failure

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Background

The current scientific data controversially indicate obesity both as a risk factor for developing congestive heart failure (CHF) and a positive prognostic factor.

Aims

The present study evaluated the impact of weight loss on clinical and instrumental parameters in a selected group of obese patients with CHF.

Methods

An overall population of 560 HF patients was sub-grouped on the basis of the Body Mass Index (BMI): 8.2% were underweight (BMI<20.7), 63.9% normal weight (BMI: 20.7–27.7), 19.6% overweight (BMI: 27.8–31), and 8.3% obese (BMI>31). Of the 46 overweight and obese patients, 28 (55.2% men, age 51–80 years) accepted a tailored low-caloric dietary program for at least 4 months. The 28 patients belonged to both obese and overweight groups (BMI>27.8) and were in NYHA classes II–III. Mean follow-up was 5 months.

Results

The mean loss of body weight was 4 kg in 81.4% of patients, versus 3 kg mean increase in whole (560 patients) population (72.5–75.5 kg). In the 28 patients we recorded a significant (p<0.05) improvement of NYHA class, better control of arterial blood pressure and statistically significant (p<0.05) lowering of total cholesterol and triglyceride levels.

Conclusions

Tailored dietetic program may improve clinical and instrumental parameters in patients with CHF.

Journal Article.  2451 words.  Illustrated.

Subjects: Cardiovascular Medicine

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