Journal Article

Left-ventricular electromechanical delay is prolonged in patients with postoperative atrial fibrillation

Yasushige Shingu, Suguru Kubota, Satoru Wakasa, Noriyoshi Ebuoka, Daisuke Mori, Tomonori Ooka, Tsuyoshi Tachibana and Yoshiro Matsui

in European Journal of Cardio-Thoracic Surgery

Published on behalf of European Association for Cardio-Thoracic Surgery

Volume 39, issue 5, pages 684-688
Published in print May 2011 | ISSN: 1010-7940
Published online May 2011 | e-ISSN: 1873-734X | DOI: http://dx.doi.org/10.1016/j.ejcts.2010.08.015
Left-ventricular electromechanical delay is prolonged in patients with postoperative atrial fibrillation

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  • Cardiovascular Medicine
  • Cardiothoracic Surgery

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Objective: Although several risk factors for postoperative atrial fibrillation (AF) have been proposed, it remains the most common complication after cardiac surgery, even in low-risk patients. There is still no single reliable and reproducible parameter for predicting AF, and no standardized recommendation exists for this issue. Electromechanical delay (excitation–contraction coupling delay) is the time delay from the electrical activation to the actual systolic motion, and it reflects abnormality in calcium-handling proteins, which is considered one mechanism of postoperative AF. We hypothesized that left-ventricular electromechanical delay (LVEMD) is correlated to postoperative AF and serially examined it by echocardiography. Methods: We prospectively included 16 patients with relatively low risk for AF, who underwent cardiac surgery. The inclusion criteria were younger than 80 years, an ejection fraction greater than 45%, a left-atrial dimension less than 50 mm, and a brain natriuretic peptide (BNP) value less than 250 pg ml−1. Postoperative AF for 10 postoperative days was monitored by 24-h electrocardiogram. The LVEMD was assessed by pulse-wave tissue Doppler echocardiography before and 1, 3, and 7 days after the operation. Serum BNP, adrenalin, and noradrenalin levels were also examined at the same time. Results: Postoperative AF was detected in six (37.5%) patients. There was no significant difference in heart rate, QRS duration, and serum hormones between the non-AF (n = 10) and AF (n = 6) groups. Although the preoperative LVEMD was comparable, that on postoperative day 1 of the AF group was significantly longer than that of the non-AF group (in the septal wall, 174 ± 50 vs 101 ± 36 ms, p = 0.020; in the lateral wall, 195 ± 71 and 111 ± 37 ms, p = 0.029). A LVEMD on postoperative day 1 greater than 150 ms well predicted postoperative AF (sensitivity, 75% and 75%; specificity, 100% and 86%, in septal and lateral LVEMDs, respectively). Conclusions: LVEMD is prolonged in patients with postoperative AF. This could be a new predicting parameter for AF in low-risk patients.

Keywords: Electromechanical delay; Atrial fibrillation; Cardiac surgery

Journal Article.  2542 words.  Illustrated.

Subjects: Cardiovascular Medicine ; Cardiothoracic Surgery

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