Journal Article

P.2. Syncope, Pacemaker, CRT & ICD

H. Kuwornu, P. Pepi, A. Reggiani, F. Cionini, L. Tomasi and R. Zanini

in EP Europace

Published on behalf of European Heart Rhythm Association of the European Society of Cardiology (ESC)

Volume 7, issue s3, pages S45-S45
Published in print October 2005 | ISSN: 1099-5129
Published online October 2005 | e-ISSN: 1532-2092 | DOI:
P.2. Syncope, Pacemaker, CRT & ICD

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We retrospectively analyzed patients treated with CRT in our centre, to evacuate the benefit of treatment.


35 patients mean age 69.8 years, with similar characteristics to the inclusion criteria described in previous randomized trials, underwent CRT. 40% of patients had back-up defibrillator. Left bundle branch block was present in 97% and atrial fibrillation in 28%. All patients were in conventional pharmacological therapy.


We found a significant improvement in the functional capacity assessed by NYHA functional class both in patients in sinus rhythm and atrial fibrillation (p < 0.001). Total mortality was 33%. We observed positive trends toward improvement of LVEF, LVEDD, therapy titration and reduction of mitral regurgitation and total mortality, without a statistical significance probably because of the low number of patients.


Our data agree with literature results about improvement of functional capacity. We treated also patients in NYHA class (who has already an indication for defibrillator implementation) and the benefit they received from treatment is in agreement with that observed in recent trials. That confirms the possibility to extend the recommendation of the use of CRT also to patients with minimal heart failure symptoms.

Journal Article.  0 words. 

Subjects: Cardiovascular Medicine

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