Journal Article

Reversible ischaemic neurological deficit associated with short-term methylphenidate medication

Christine Leonhard, Andreas Reif, Marcus Beck, Christian Jacob and Klaus-Peter Lesch

in International Journal of Neuropsychopharmacology

Published on behalf of International College of Neuropsychopharmacology

Volume 9, issue 1, pages 129-130
Published in print February 2006 | ISSN: 1461-1457
Published online February 2006 | e-ISSN: 1469-5111 | DOI: http://dx.doi.org/10.1017/S1461145705005596
Reversible ischaemic neurological deficit associated with short-term methylphenidate medication

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Abstract

Methylphenidate is a central nervous system stimulant pharmacologically related to amphetamines frequently used in attention deficit hyperactivity disorder (ADHD) and narcolepsy. Haemorrhagic stroke is a rare but well-known potential side-effect of amphetamine abuse, however, cerebral ischaemia has been reported casuistically (Rothrock et al., 1988). Here, we present incidence of a reversible ischaemic neurological deficit during short-term methylphenidate treatment.

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