Journal Article

Dual chamber pacing with optimal AV delay in congestive heart failure

A. Capucci, S. Romano, A. Puglisi, M. Santini, M. Pagani, R. Cazzin, D. Zanuttini, S. Mangiameli, P.V. Moracchini, R. Neri, P. De Ciuceis, A. Circo, S. Cavaglià and F. De Seta

in EP Europace

Published on behalf of European Heart Rhythm Association of the European Society of Cardiology (ESC)

Volume 1, issue 3, pages 174-178
Published in print July 1999 | ISSN: 1099-5129
Published online July 1999 | e-ISSN: 1532-2092 | DOI:
Dual chamber pacing with optimal AV delay in congestive heart failure

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A prospective randomized trial was set up to evaluate contractile parameters and quality of life in patients with congestive heart failure.

Methods and Results

We describe the results from 38 patients in sinus rhythm and with chronic heart failure due to congestive cardiomyopathy, prospectively randomized to optimal medical therapy (Group 1, 19 patients) or optimal medical therapy plus dual chamber pacemaker programmed to optimal AV delay (Group 2, 19 patients).

At a 6 month follow-up, 7/19 patients in Group 1 had died compared with 5/19 patients in Group 2. During follow-up, there were few significant changes in evaluated parameters except for mitral regurgitation time, which was prolonged in Group 1 and shortened in Group 2. The systolic left ventricular diameter shortened significantly only in Group 2. An energy and activity questionnaire showed that the eVect of DDD pacing in the latter patient population was beneficial.


From these results we may conclude that at the 6 month follow-up DDD pacing with echo-optimized AV interval programming can improve quality of life without affecting survival.

Keywords: Congestive heart failure; dilated cardiomyopathy; dual chamber pacing

Journal Article.  0 words. 

Subjects: Cardiovascular Medicine

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