Journal Article

Reproducibility of asystole during head-up tilt testing in patients with neurally mediated syncope

G. Foglia-Manzillo, M. Romanò, G. Corrado, L. M. Tagliagambe, G. Tadeo, M. Spata, A. Spinelli, A. Grieco and M. Santarone

in EP Europace

Published on behalf of European Heart Rhythm Association of the European Society of Cardiology (ESC)

Volume 4, issue 4, pages 365-367
Published in print October 2002 | ISSN: 1099-5129
Published online October 2002 | e-ISSN: 1532-2092 | DOI: http://dx.doi.org/10.1053/eupc.2002.0260
Reproducibility of asystole during head-up tilt testing in patients with neurally mediated syncope

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Tilt induced prolonged asystole has been considered to identify a distinct subgroup of patients with neurally mediated syncope and management including permanent pacemaker implantation has been suggested. To evaluate the reproducibility of asystolic response during head-up tilt testing (HUT), 33 patients with neurally mediated syncope and asystolic response (≥3 seconds) during HUT prospectively underwent two consecutive tests 13±15 days apart. On repeat tilt testing asystole was reproduced in 12 patients (36%), while 8 patients still had a positive HUT, but without asystole. Remarkably, 13 patients (40%) had a negative repeat HUT. Among 12 patients with asystole on both HUTs there was no significant difference in duration of asystole (14 371±11 430 ms vs 13 707±10 470 ms,P =ns) and time to syncope (36±20 min vs 37±20 min, P=ns) during initial and repeat HUTs. In conclusion, asystole during tilt testing does not seem to be a reproducible response.

Keywords: Head-up tilt test; asystole; reproducibility

Journal Article.  0 words. 

Subjects: Cardiovascular Medicine

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