Journal Article

An Outbreak of Acute Respiratory Disease Caused by <i>Mycoplasma pneumoniae</i> and Adenovirus at a Federal Service Training Academy: New Implications from an Old Scenario

Daniel R. Feikin, John F. Moroney, Deborah F. Talkington, W. Lanier Thacker, James E. Code, Lori A. Schwartz, Dean D. Erdman, Jay C. Butler and Martin S. Cetron

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 29, issue 6, pages 1545-1550
Published in print December 1999 | ISSN: 1058-4838
Published online December 1999 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/313500
An Outbreak of Acute Respiratory Disease Caused by Mycoplasma pneumoniae and Adenovirus at a Federal Service Training Academy: New Implications from an Old Scenario

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Outbreaks of Mycoplasma pneumoniae and adenovirus have been reported in military institutions for several decades. During a recent outbreak in a federal service training academy, we performed an epidemiological and laboratory investigation to better characterize and control the outbreak. Of 586 students responding to a questionnaire, 317 (54%) reported having a respiratory illness during the outbreak period. Among 42 students who underwent complete laboratory testing, 24 (57%) had evidence of M. pneumoniae infection, 8 (19%) had evidence of adenovirus infection, and 4 (10%) had evidence of both. Polymerase chain reaction testing of oropharyngeal swabs revealed more acute M. pneumoniae infections (57% positive) than did serology or culture. Multivariate analysis revealed that visiting the campus health clinic >3 times for a nonrespiratory condition, such as injury, was a significant risk factor for illness among freshmen early in the course of the outbreak, whereas having an ill roommate was a risk factor throughout the duration of the outbreak.

Journal Article.  4029 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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