Journal Article

Spectrum of Opportunistic Infections and Malignancies in Patients with Human Immunodeficiency Virus Infection in South Korea

Myoung-don Oh, Sang Won Park, Hong Bin Kim, Ui Seok Kim, Nam Joong Kim, Hee Jung Choi, Dong Hyeon Shin, Joo Shil Lee and Kangwon Choe

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 29, issue 6, pages 1524-1528
Published in print December 1999 | ISSN: 1058-4838
Published online December 1999 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/313516
Spectrum of Opportunistic Infections and Malignancies in Patients with Human Immunodeficiency Virus Infection in South Korea

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To determine the frequency and types of major opportunistic diseases in patients with HIV infection in South Korea, we reviewed the medical records of 173 HIV-infected patients. The patients were seen from 1985 to 1998 at a referral hospital for AIDS in South Korea. Most patients (85%) were male, and 107 (62%) were infected by heterosexual contacts. CD4+ lymphocyte counts at presentation were <200/µL in 27% of the patients. Tuberculosis was the most frequent opportunistic infection (25% of patients), followed by candidiasis (21%), herpes zoster (20%), Pneumocystis carinii pneumonia (10%), cytomegalovirus disease (9.8%). There were no cases of toxoplasmosis. Kaposi's sarcoma developed in 3 patients (1.7%), and non-Hodgkin's lymphoma, in 2 (1.2%). Eleven patients (6.4%) developed peripheral neuropathy, and 8 (4.6%) had HIV encephalopathy. Tuberculosis was the single most important HIV-related infection in South Korean patients.

Journal Article.  2561 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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