Journal Article

An Outbreak of <i>Streptococcus pneumoniae</i> Serotype 1 in a Closed Community in Southern Israel

Ron Dagan, Serge Gradstein, Ilana Belmaker, Nurith Porat, Yaffa Siton, Gabriel Weber, Jacob Janco and Pablo Yagupsky

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 30, issue 2, pages 319-321
Published in print February 2000 | ISSN: 1058-4838
Published online February 2000 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/313645
An Outbreak of Streptococcus pneumoniae Serotype 1 in a Closed Community in Southern Israel

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An outbreak of Streptococcus pneumoniae serotype 1 occurred in a closed community that was characterized by poverty and crowding. Vaccine was administered to individuals aged >2 years; no new cases occurred among vaccine recipients. Six weeks after vaccination, carriage of serotype 1, but not of other serotypes, decreased 8.8-fold. This suggests that the reduction in serotype 1 carriage reflects the natural course of the outbreak rather than a vaccine effect. Polysaccharide vaccine may be helpful in terminating pneumococcal outbreaks but may not affect pneumococcal carriage.

Journal Article.  1559 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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