Journal Article

Treatment of Cutaneous Larva Migrans

Eric Caumes

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 30, issue 5, pages 811-814
Published in print May 2000 | ISSN: 1058-4838
Published online May 2000 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/313787
Treatment of Cutaneous Larva Migrans

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Cutaneous larva migrans caused by the larvae of animal hookworms is the most frequent skin disease among travelers returning from tropical countries. Complications (impetigo and allergic reactions), together with the intense pruritus and the significant duration of the disease, make treatment mandatory. Freezing the leading edge of the skin track rarely works. Topical treatment of the affected area with 10%–15% thiabendazole solution or ointment has limited value for multiple lesions and hookworm folliculitis, and requires applications 3 times a day for at least 15 days. Oral thiabendazole is poorly effective when given as a single dose (cure rate, 68%–84%) and is less well tolerated than either albendazole or ivermectin. Treatment with a single 400-mg oral dose of albendazole gives cure rates of 46%–100%; a single 12-mg oral dose of ivermectin gives cure rates of 81%–100%.

Journal Article.  2335 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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