Journal Article

Rapid Progressive Subacute Sclerosing Panencephalitis in a 2-Year-Old Child with Congenital Athyreosis

Gerd M. Lackmann, Martin Hannen, Faramarz Madjlessi, Hans G. Lenard and Horst Schroten

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 31, issue 1, pages 196-199
Published in print July 2000 | ISSN: 1058-4838
Published online July 2000 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/313917
Rapid Progressive Subacute Sclerosing Panencephalitis in a 2-Year-Old Child with Congenital Athyreosis

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We present the unique case of a 2-year-old girl with congenital athyreosis who acquired primary measles virus infection at the age of 18 months, coincidentally with an Epstein-Barr virus infection. First neurologic symptoms of subacute sclerosing panencephalitis appeared 5 months later, and the girl died within 6 months after a rapid progressive illness. Factors possibly predisposing to this extraordinary disease course—primary measles virus infection at an early age and lack of evidence for immuno-deficiency—are discussed.

Journal Article.  1652 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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