Journal Article

Reactogenicity and Immunogenicity of a Lyme Disease Vaccine in Children 2–5 Years Old

J. Beran, N. De Clercq, I. Dieussaert and Christian Van Hoecke

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 31, issue 6, pages 1504-1507
Published in print December 2000 | ISSN: 1058-4838
Published online December 2000 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/317479
Reactogenicity and Immunogenicity of a Lyme Disease Vaccine in Children 2–5 Years Old

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Two doses of a recombinant Lyme disease vaccine (15 and 30 µg) were administered to children 2–5 years old (0–1-month schedule) and were well tolerated. Both doses were highly immunogenic with geometric mean titers 1 month after vaccination of 4366 and 9877 ELISA units (EU)/mL, respectively. Nearly all subjects had antibody levels of ⩾1400 EU/mL, suggesting protective tick titre for one tick season.

Journal Article.  2906 words. 

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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