Journal Article

Active Tuberculosis in Individuals Infected with Human Immunodeficiency Virus after Isoniazid Prophylaxis

Daniel W. Fitzgerald, Michelle Marie Morse, Jean William Pape and Warren D. Johnson

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 31, issue 6, pages 1495-1497
Published in print December 2000 | ISSN: 1058-4838
Published online December 2000 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/317485
Active Tuberculosis in Individuals Infected with Human Immunodeficiency Virus after Isoniazid Prophylaxis

More Like This

Show all results sharing these subjects:

  • Infectious Diseases
  • Immunology
  • Public Health and Epidemiology
  • Microbiology

GO

Show Summary Details

Preview

A review was conducted in Haiti to determine the timing and outcome of active tuberculosis (TB) in human immunodeficiency virus (HIV)-positive patients who had previously received isoniazid (INH) prophylaxis. Of 1005 HIV-seropositive patients who completed INH prophylaxis, 14 (1.4%) subsequently had active TB diagnosed. The median interval between discontinuation of INH prophylaxis and TB diagnosis was 8 months for 6 patients receiving 6 months of INH, 22 months for 5 patients receiving 12–24 months of INH, and 40 months for 3 patients receiving 24–36 months of INH (P = .026). There is a postprophylaxis effect on INH that is dependent upon the duration of therapy.

Journal Article.  1746 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

Full text: subscription required

How to subscribe Recommend to my Librarian

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.