Journal Article

Incidence of Imipenem Hypersensitivity Reactions in Febrile Neutropenic Bone Marrow Transplant Patients with a History of Penicillin Allergy

Scott A. McConnell, S.R. Penzak, T.S. Warmack, E.J. Anaissie and P.O. Gubbins

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 31, issue 6, pages 1512-1514
Published in print December 2000 | ISSN: 1058-4838
Published online December 2000 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/317507
Incidence of Imipenem Hypersensitivity Reactions in Febrile Neutropenic Bone Marrow Transplant Patients with a History of Penicillin Allergy

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The purpose of this retrospective study was to assess cross-hypersensitivity between imipenem/cilastatin and penicillin in patients with reported penicillin allergies. Medical records of febrile neutropenic, penicillin-allergic bone marrow transplant recipients who received imipenem/cilastatin treatment were retrospectively reviewed. The findings of this study indicate the incidence of cross-reactivity between imipenem/cilastatin and penicillin among patients with a history of penicillin allergy may be lower than previously reported.

Journal Article.  2312 words. 

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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