Journal Article

Progressive Multifocal Leukoencephalopathy and Idiopathic CD4<sup>+</sup>Lymphocytopenia: A Case Report and Review of Reported Cases

S. Haider, D. Nafziger, J. A. Gutierrez, I. Brar, N. Mateo and J. Fogle

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 31, issue 4, pages e20-e22
Published in print October 2000 | ISSN: 1058-4838
Published online October 2000 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/318120
Progressive Multifocal Leukoencephalopathy and Idiopathic CD4+Lymphocytopenia: A Case Report and Review of Reported Cases

More Like This

Show all results sharing these subjects:

  • Infectious Diseases
  • Immunology
  • Public Health and Epidemiology
  • Microbiology

GO

Show Summary Details

Preview

Progressive multifocal leukoencephalopathy (PML) is a well recognized demyelinating neurological disorder caused by JC virus. Idiopathic CD4+ lymphocytopenia (ICL) is a syndrome first described by the Centers for Disease Control and Prevention as a CD4+ count <300 cells/mm3 or a CD4+ count that is <20% of the total T cell count on 2 occasions, with no evidence of human immunodeficiency virus (HIV) infection on testing, and absence of any defined immunodeficiency or therapy that depresses the levels of CD4+ T cells. To the best of our knowledge, this is the third reported case of PML and ICL, and also the first reported case of the use of cidofovir to treat PML in a patient not infected with human immunodeficiency virus.

Journal Article.  1303 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

Full text: subscription required

How to subscribe Recommend to my Librarian

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.