Journal Article

Azithromycin and Gentamicin Therapy for the Treatment of Humans with Brucellosis

Javier Solera, José L. Beato, Elisa Martínez-Alfaro, Juan C. Segura and Elena de Tomas

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 32, issue 3, pages 506-509
Published in print February 2001 | ISSN: 1058-4838
Published online February 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/318503
Azithromycin and Gentamicin Therapy for the Treatment of Humans with Brucellosis

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Ten patients with brucellosis were treated with azithromycin and gentamicin to assess the treatment's safety and efficacy. Seven patients had an excellent therapeutic response at the end of therapy; however, relapse was noted in 3. When relapse was considered in combination with an initial lack of efficacy, 5 patients (50%; 95% confidence interval, 18.7%–81.3%) did not respond to therapy; these results do not favor the use of azithromycin to treat brucellosis in humans.

Journal Article.  2382 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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