Journal Article

Influence of Highly Active Antiretroviral Therapy on the Outcome of Subclinical Visceral Leishmaniasis in Human Immunodeficiency Virus-Infected Patients

Rafael de la Rosa, Juan A. Pineda, Juan Delgado, Juan Macías, Francisco Morillas, Joaquina Martín-Sánchez, Manuel Leal, Armando Sánchez-Quijano and Eduardo Lissen

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 32, issue 4, pages 633-635
Published in print February 2001 | ISSN: 1058-4838
Published online February 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/318708
Influence of Highly Active Antiretroviral Therapy on the Outcome of Subclinical Visceral Leishmaniasis in Human Immunodeficiency Virus-Infected Patients

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Seventeen human immunodeficiency virus-infected patients who were harboring untreated subclinical visceral leishmaniasis (VL) were prospectively followed up. None of the 11 patients who received highly active antiretroviral therapy (HAART) presented with symptomatic VL during follow-up, whereas 2 out of 6 patients who received therapy other than HAART had an episode of overt kala-azar. These findings suggest that HAART does not induce the evolution of latent VL into symptomatic disease.

Journal Article.  1805 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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