Journal Article

Inactivated Pronase as the Cause of False-Positive Results of Serum Cryptococcal Antigen Tests

Thomas C. Stoeckli and William J. Burman

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 32, issue 5, pages 836-837
Published in print March 2001 | ISSN: 1058-4838
Published online March 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/319212
Inactivated Pronase as the Cause of False-Positive Results of Serum Cryptococcal Antigen Tests

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Four patients who had acquired immunodeficiency syndrome and who were evaluated for headache within a 3-week period had false-positive results of serum cryptococcal antigen tests. This cluster of false-positive test results appeared to be due to inactivation of the pronase vial in the test kit, a cause that has not been reported previously.

Journal Article.  1170 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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