Journal Article

Epidemic Typhus Meningitis in the Southwestern United States

Robert F. Massung, Larry E. Davis, Kim Slater, Donald B. McKechnie and Marion Puerzer

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 32, issue 6, pages 979-982
Published in print March 2001 | ISSN: 1058-4838
Published online March 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/319351
Epidemic Typhus Meningitis in the Southwestern United States

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A patient residing in New Mexico had murine typhus diagnosed. A novel molecular assay was performed at the Centers for Disease Control and Prevention, and Rickettsia prowazekii, the agent of epidemic typhus, was found, rather than R. Typhi. To our knowledge, this is the first reported case of epidemic typhus confirmed by means of polymerase chain reaction-based testing of cerebrospinal fluid, and it introduces a novel assay for the molecular diagnosis of both epidemic and murine typhus.

Journal Article.  2666 words. 

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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