Journal Article

Encephalitis without Meningitis Due to Sandfly Fever Virus Serotype Toscana

Daniele Dionisio, Marcello Valassina, Maria Grazia Ciufolini, Angela Vivarelli, Francesco Esperti, Maria Grazia Cusi, Antonella Marchi, Franca Mazzoli and Cinzia Lupi

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 32, issue 8, pages 1241-1243
Published in print April 2001 | ISSN: 1058-4838
Published online April 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/319759
Encephalitis without Meningitis Due to Sandfly Fever Virus Serotype Toscana

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The role of Toscana (TOS) virus in producing encephalitis without meningitis is uncertain. We studied 2 cases of TOS virus encephalitis without meningitis by means of nested polymerase chain reaction assay and DNA sequencing. Findings confirm that TOS virus may directly cause encephalitis and suggest the usefulness of DNA sequencing in investigating relationships between TOS virus molecular patterns and the spectrum of neurological involvement.

Journal Article.  2358 words. 

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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