Journal Article

<i>Streptococcus intermedius, Streptococcus constellatus</i>, and <i>Streptococcus anginosus</i> (“Streptococcus milleri Group”) Are of Different Clinical Importance and Are Not Equally Associated with Abscess

Jill E. Clarridge, Silvia Attorri, Daniel M. Musher, Jeff Hebert and Sherry Dunbar

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 32, issue 10, pages 1511-1515
Published in print May 2001 | ISSN: 1058-4838
Published online May 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/320163
Streptococcus intermedius, Streptococcus constellatus, and Streptococcus anginosus (“Streptococcus milleri Group”) Are of Different Clinical Importance and Are Not Equally Associated with Abscess

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Difficulties in distinguishing organisms of the “Streptococcus milleri group” (SMG; Streptococcus intermedius, Streptococcus constellatus, and Streptococcus anginosus), have caused ambiguity in determining their pathogenic potential. We reviewed 118 cases in which SMG isolates had been identified using 16S rDNA sequence. S. constellatus and S. anginosus were isolated far more frequently than was S. intermedius. Nearly all isolates of S. intermedius and most isolates of S. constellatus, but only 19% of those of S. anginosus, were associated with abscess. Our findings suggest that speciation of the SMG may guide diagnostic evaluation, give insight into the possible role of coinfecting organisms, and help assess the need to search for occult abscess.

Journal Article.  3153 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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