Journal Article

Iron Status and Indicators of Human Immunodeficiency Virus Disease Severity among Pregnant Women in Malawi

Richard D. Semba, Taha E. Taha, Newton Kumwenda, Laban Mtimavalye, Robin Broadhead, Paolo G. Miotti and John D. Chiphangwi

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 32, issue 10, pages 1496-1499
Published in print May 2001 | ISSN: 1058-4838
Published online May 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/320167
Iron Status and Indicators of Human Immunodeficiency Virus Disease Severity among Pregnant Women in Malawi

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The relationships among hemoglobin, ferritin, and transferrin receptor levels and 2 markers of human immunodeficiency virus (HIV) disease severity—HIV load and CD4+ lymphocyte count—were characterized among 483 pregnant women in Malawi, Africa. The only significant correlation was an inverse correlation between hemoglobin level and plasma HIV load (r = −.104; P<.03). The prevalence of iron deficiency anemia was not significantly different across quartiles of HIV load or CD4+ lymphocyte count. In contrast to previous studies, these data suggest that iron status is not related to markers of HIV disease severity in pregnant women in Africa.

Journal Article.  2177 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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