Journal Article

Medullary Gnathostomiasis in a White Patient: Use of Immunodiagnosis and Magnetic Resonance Imaging

J. Chandenier, J. Husson, S. Canaple, C. Gondry-Jouet, P. Dekumyoy, M. Danis, G. Riveau, C. Hennequin, A. Rosa and C. P. Raccurt

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 32, issue 11, pages e154-e157
Published in print June 2001 | ISSN: 1058-4838
Published online June 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/320520
Medullary Gnathostomiasis in a White Patient: Use of Immunodiagnosis and Magnetic Resonance Imaging

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A 48-year-old French diplomat presented with a sensory-motor paraparesis of rapid onset, leading to paraplegia. Successive magnetic resonance image scans showed lesions of the thoracic spinal cord that were at different levels from one examination to the next. Specific anti-gnathostome antibodies were detected by means of enzyme-linked immunosorbent assay and Western blot test in both plasma and cerebrospinal fluid. Albendazole treatment prevented disease progression, but only partial regression of the neurologic symptoms was obtained.

Journal Article.  2629 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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