Journal Article

Clinical Features of Paragonimiasis Cases Recently Found in Japan: Parasite-Specific Immunoglobulin M and G Antibody Classes

Fukumi Nakamura-Uchiyam, N. Onah and Yukifumi Nawa

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 32, issue 12, pages e171-e175
Published in print June 2001 | ISSN: 1058-4838
Published online June 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/320750
Clinical Features of Paragonimiasis Cases Recently Found in Japan: Parasite-Specific Immunoglobulin M and G Antibody Classes

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We retrospectively analyzed clinical features in 30 patients who were referred to our laboratory and given a diagnosis of Paragonimus westermani infection in 1999. Our results indicate that pleurisy with eosinophilia and dominant immunoglobulin (Ig) M antibody are characteristic features of the early stage of paragonimiasis, whereas IgG antibody is dominant in the late stage. Thus, in addition to tests for parasite-specific IgG antibody, tests for IgM-class antibody should always be considered for patients with pleurisy in whom paragonimiasis is suspected.

Journal Article.  2675 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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