Journal Article

Prevalence of the T215Y Mutation in Human Immunodeficiency Virus Type 1-Infected Pregnant Women in a New York Cohort, 1995–1999

Yekaterina Sitnitskaya, Gemma Rochford, Mona Rigaud, Shaffiq Essajee, Henry Pollack, Keith Krasinski and William Borkowsky

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 33, issue 1, pages e3-e7
Published in print July 2001 | ISSN: 1058-4838
Published online July 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/320877
Prevalence of the T215Y Mutation in Human Immunodeficiency Virus Type 1-Infected Pregnant Women in a New York Cohort, 1995–1999

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From 1997 through 1999, the prevalence of the zidovudine resistance mutation T215Y was 9.7% among pregnant women, and the human immunodeficiency virus type 1 (HIV-1) load in those with resistant virus was higher than that measured in women with wild-type HIV-1. All mutations were noted in women with zidovudine experience, which suggests that monotherapy may not be adequate prophylaxis for vertical transmission of HIV-1 infection in the current era.

Journal Article.  3334 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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