Journal Article

Investigation of Primary Human Immunodeficiency Virus Infection in Patients Who Test Positive for Heterophile Antibody

Rochelle P. Walensky, Eric S. Rosenberg, Mary Jane Ferraro, Elena Losina, Bruce D. Walker and Kenneth A. Freedberg

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 33, issue 4, pages 570-572
Published in print August 2001 | ISSN: 1058-4838
Published online August 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/321903
Investigation of Primary Human Immunodeficiency Virus Infection in Patients Who Test Positive for Heterophile Antibody

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In light of a recent report of 3 false-positive results of Epstein-Barr virus heterophile tests caused by HIV infection, we sought to assess the frequency of this occurrence. One hundred thirty-two positive heterophile antibody-tested serum samples were obtained from 2 tertiary care facilities in Boston to assess for HIV, and all tested negative for HIV plasma RNA. This study shows that false-positive results of heterophile tests are not frequently associated with primary HIV infection.

Journal Article.  1466 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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