Journal Article

Age as a Risk Factor for Severe <i>Plasmodium falciparum</i> Malaria in Nonimmune Patients

Eli Schwartz, Siegal Sadetzki, Havi Murad and David Raveh

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 33, issue 10, pages 1774-1777
Published in print November 2001 | ISSN: 1058-4838
Published online November 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/322522
Age as a Risk Factor for Severe Plasmodium falciparum Malaria in Nonimmune Patients

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In this nationwide, cross-sectional study, we evaluated the influence of age and other factors that affect clinical outcome of Plasmodium falciparum malaria in nonimmune patients. Of 135 patients with P. falciparum malaria, 84 (62%) were <40 years old, and only 5% of the patients in this age group developed severe malaria, compared with 18% of the subjects who were ⩽40 years of age (odds ratio, 4.29); moreover, all deaths occurred in the latter group. Male subjects did not differ from female subjects with regard to severity of disease.

Journal Article.  2415 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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