Journal Article

Prospective Assessment of the Etiology of Acute Febrile Illness after a Tick Bite in Slovenia

Stanka Lotrič-Furlan, Miroslav Petrovec, Tatjana Avsic-Zupanc, William L. Nicholson, John W. Sumner, James E. Childs and Franc Strle

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 33, issue 4, pages 503-510
Published in print August 2001 | ISSN: 1058-4838
Published online August 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/322586
Prospective Assessment of the Etiology of Acute Febrile Illness after a Tick Bite in Slovenia

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A prospective study established the etiology of febrile illnesses in residents of Slovenia that occurred within 6 weeks after a tick bite. A combination of laboratory and clinical criteria identified 64 (49.2%) of 130 patients as having confirmed, probable, or possible cases of tickborne disease during 1995 and 1996. Of the 130 patients, 36 (27.7%) had laboratory evidence of tickborne encephalitis, all of whom had clinically confirmed disease. Evidence of infection with Borrelia burgdorferi sensu lato was identified in 26 patients; 10 (7.7%) had confirmed Lyme borreliosis. Of 22 patients with evidence of Ehrlichia phagocytophila infection, 4 (3.1%) had confirmed ehrlichiosis. Infection by multiple organisms was found in 19 (14.6%) of 130 patients. Patients with meningeal involvement (43 [72.3%] of 59) were more likely to have confirmed tickborne disease than were patients with illness of undefined localization (18 [26.5%] of 68; P < .0001). Tickborne viral and bacterial infections are an important cause of febrile illness in Slovenia.

Journal Article.  5042 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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