Journal Article

Systemic Inflammatory Response Syndrome in Adult Patients with Nosocomial Bloodstream Infection Due to <i>Staphylococcus aureus</i>

Hilmar Wisplinghoff, Harald Seifert, Marcus Coimbra, Richard P. Wenzel and Michael B. Edmond

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 33, issue 5, pages 733-736
Published in print September 2001 | ISSN: 1058-4838
Published online September 2001 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1086/322610
Systemic Inflammatory Response Syndrome in Adult Patients with Nosocomial Bloodstream Infection Due to Staphylococcus aureus

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To determine the impact of methicillin resistance on clinical course and outcome, we evaluated nosocomial bloodstream infections (BSIs) due to Staphylococcus aureus that were diagnosed in 82 adult patients at the Medical College of Virginia Hospitals from December 1995 through May 1997. Patients with BSI due to methicillin-resistant S. aureus were compared with patients with BSI due to methicillin-susceptible S. aureus; the groups did not differ with regard to inflammatory response or outcome. Mortality was predicted by systemic inflammatory response and Acute Physiology and Chronic Health Evaluation II score but did not correlate with bacterial resistance to methicillin.

Journal Article.  2550 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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