Journal Article

Two Episodes of Leukoencephalitis Associated with Recombinant Hepatitis B Vaccination in a Single Patient

Demetrios Konstantinou, Christos Paschalis, Theodoros Maraziotis, Panagiotis Dimopoulos, Harry Bassaris and Athanasios Skoutelis

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 33, issue 10, pages 1772-1773
Published in print November 2001 | ISSN: 1058-4838
Published online November 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/322617
Two Episodes of Leukoencephalitis Associated with Recombinant Hepatitis B Vaccination in a Single Patient

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Cases of central nervous system demyelination have been reported after recombinant hepatitis B vaccination, but no causal link has been clearly demonstrated. We present the first case report involving the occurrence of 2 episodes of leukoencephalitis in a previously healthy patient after vaccination and rechallenge with hepatitis B vaccine.

Journal Article.  1068 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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