Journal Article

Prophylaxis Failure Is Associated with a Specific <i>Pneumocystis carinii</i> Genotype

Philippe M. Hauser, Philippe Sudre, Aimable Nahimana and Patrick Francioli

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 33, issue 7, pages 1080-1082
Published in print October 2001 | ISSN: 1058-4838
Published online October 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/322659
Prophylaxis Failure Is Associated with a Specific Pneumocystis carinii Genotype

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To investigate the possible association between Pneumocystis carinii types and various clinical and demographic parameters, we used molecular typing to analyze 93 bronchoalveolar lavage specimens from patients with P. carinii pneumonia (PCP). Multivariate regression analysis revealed an association between being infected with a specific P. carinii genotype and receiving anti-PCP prophylaxis (odds ratio, 4.4; 95% confidence interval, 1.0–18.6; P = .05), although no association with a specific drug was detected.

Journal Article.  1625 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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