Journal Article

Emergence of Rifampin-Resistant <i>Streptococcus pneumoniae</i> as a Result of Antimicrobial Therapy for Penicillin-Resistant Strains

Peter M. B. van Tilburg, Debby Bogaert, Marcel Sluijter, Arjan R. Jansz, Ronald de Groot and Peter W. M. Hermans

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 33, issue 8, pages e93-e96
Published in print October 2001 | ISSN: 1058-4838
Published online October 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/323021
Emergence of Rifampin-Resistant Streptococcus pneumoniae as a Result of Antimicrobial Therapy for Penicillin-Resistant Strains

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A multidrug-resistant strain of Streptococcus pneumoniae was isolated in The Netherlands during a nosocomial outbreak among 36 patients who mainly had chronic obstructive pulmonary disease. After the commencement of barrier nursing and short-term ceftriaxone-rifampin eradication therapy, the epidemic ceased. However, eradication therapy failed in 3 patients, and follow-up investigation of these patients showed the emergence of rifampin-resistant isolates.

Journal Article.  2283 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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