Journal Article

The Influence of Tumor Necrosis Factor–α and Interleukin-10 Gene Promoter Polymorphism on the Inflammatory Response in Experimental Human Endotoxemia

J. W. Fijen, J. E. Tulleken, B. G. Hepkema, T. S. van der Werf, J. J. M. Ligtenberg and J. G. Zijlstra

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 33, issue 9, pages 1601-1603
Published in print November 2001 | ISSN: 1058-4838
Published online November 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/323197
The Influence of Tumor Necrosis Factor–α and Interleukin-10 Gene Promoter Polymorphism on the Inflammatory Response in Experimental Human Endotoxemia

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In this study, we show that there is no correlation between tumor necrosis factor–α gene promoter polymorphism at position -308, interleukin-10 gene promoter polymorphism at position -1082, and the cytokine levels they produce in the human endotoxemia model.

Journal Article.  1912 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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