Journal Article

Detection of <i>Mycoplasma pneumoniae</i> DNA in Cerebrospinal Fluid of a Patient with <i>M. pneumoniae</i> Infection—"Associated" Stroke

Claudio S. Padovan, Hans-Walter Pfister, Sandra Bense, Volker Fingerle and Marianne Abele Horn

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 33, issue 10, pages e119-e121
Published in print November 2001 | ISSN: 1058-4838
Published online November 2001 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1086/323461
Detection of Mycoplasma pneumoniae DNA in Cerebrospinal Fluid of a Patient with M. pneumoniae Infection—"Associated" Stroke

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A 36-year-old woman presented with an acute ischemic stroke and a concomitant Mycoplasma pneumoniae infection that had been proven clinically, bacteriologically, and serologically. M. pneumoniae DNA was demonstrated in cerebrospinal fluid by positive nested polymerase chain reaction, and intrathecal antibody production was also detected. Contrary to previous reports about M. pneumoniae–associated stroke, most thrombostatic abnormalities in this patient occurred after stroke onset. Although the cause of stroke remains unclear in this patient, central nervous system invasion of M. pneumoniae DNA has to be considered a possible cause in rare cases of cerebral ischemia.

Journal Article.  2034 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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