Journal Article

Failure of Multiple-Site Intradermal Postexposure Rabies Vaccination in Patients with Human Immunodeficiency Virus with Low CD4<sup>+</sup> T Lymphocyte Counts

Terapong Tantawichien, Wipaporn Jaijaroensup, Pakamatz Khawplod and Visith Sitprija

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 33, issue 10, pages e122-e124
Published in print November 2001 | ISSN: 1058-4838
Published online November 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/324087
Failure of Multiple-Site Intradermal Postexposure Rabies Vaccination in Patients with Human Immunodeficiency Virus with Low CD4+ T Lymphocyte Counts

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Human immunodeficiency virus (HIV)–infected patients with low CD4+ T lymphocyte counts had a poor neutralizing antibody response to pre- and postexposure rabies vaccination. This study of HIV-infected patients with CD4+ T lymphocyte counts <200/μL indicated that patients had a poor response after 4-site intradermal vaccinations (4-4-4-0-2-2, doubling the intradermal doses of cell-culture rabies vaccine).

Journal Article.  1316 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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