Journal Article

Three-Year Experience with 4-Site Intradermal Booster Vaccination with Rabies Vaccine for Postexposure Prophylaxis

Terapong Tantawichien, Thanphet Tantawichien, Chalida Supit, Pakamatz Khawplod and Visith Sitprija

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 33, issue 12, pages 2085-2087
Published in print December 2001 | ISSN: 1058-4838
Published online December 2001 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/338155
Three-Year Experience with 4-Site Intradermal Booster Vaccination with Rabies Vaccine for Postexposure Prophylaxis

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For booster vaccination of previously immunized persons with potential exposure to rabies, the World Health Organization recommends 2 doses of cell-culture vaccine administered intramuscularly or intradermally on days 0 and 3. We believe that four 0.1-mL intradermal booster doses given on a single day could be used at no risk to the recipient. We studied use of a single booster vaccination on day 0 followed by four 0.1-mL intradermal doses of cell-culture rabies vaccines, and we determined that this is a safe, convenient, and economical regimen for postexposure treatment of previously vaccinated individuals.

Journal Article.  1413 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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