Journal Article

Discontinuation of Secondary Prophylaxis in Patients with Cytomegalovirus Retinitis Who Have Responded to Highly Active Antiretroviral Therapy

Juan Berenguer, Juan González, Federico Pulido, Belén Padilla, José Luis Casado, Rafael Rubio and José Rarmón Arribas

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 34, issue 3, pages 394-397
Published in print February 2002 | ISSN: 1058-4838
Published online February 2002 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/338401
Discontinuation of Secondary Prophylaxis in Patients with Cytomegalovirus Retinitis Who Have Responded to Highly Active Antiretroviral Therapy

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We performed a prospective study of discontinuation of secondary prophylaxis against cytomegalovirus (CMV) in 36 patients with acquired immunodeficiency syndrome and quiescent CMV retinitis after successful treatment with highly active antiretroviral therapy (HAART). No reactivation or progression of retinitis was observed in 35 patients with persistent response to HAART, findings that support the discontinuation of secondary prophylaxis against CMV retinitis in such patients.

Journal Article.  2382 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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