Journal Article

Pediatric Acute Hemorrhagic Leukoencephalitis: Report of a Surviving Patient and Review

John A. D. Leake, Glenn F. Billman, Mark P. Nespeca, Susan E. Duthie, Christopher E. Dory, Hal S. Meltzer and John S. Bradley

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 34, issue 5, pages 699-703
Published in print March 2002 | ISSN: 1058-4838
Published online March 2002 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/338718
Pediatric Acute Hemorrhagic Leukoencephalitis: Report of a Surviving Patient and Review

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Acute hemorrhagic leukoencephalitis (AHLE) is a rare, fulminant CNS demyelinating condition usually diagnosed at autopsy. We report the clinical, laboratory, radiographic, and pathologic features of the first nonfatal case of pediatric AHLE confirmed by brain biopsy. Pathologic diagnosis of this condition may be critical to exclude more-common processes and to expedite the decision to administer high-dose corticosteroid therapy, which is potentially lifesaving.

Journal Article.  2399 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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