Journal Article

Tuberculosis Outbreak in a Housing Unit for Human Immunodeficiency Virus—Infected Patients in a Correctional Facility: Transmission Risk Factors and Effective Outbreak Control

Janet C. Mohle-Boetani, Vanessa Miguelino, Daniel H. Dewsnup, Edward Desmond, Evalyn Horowitz, Stephen H. Waterman and Joseph Bick

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 34, issue 5, pages 668-676
Published in print March 2002 | ISSN: 1058-4838
Published online March 2002 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/338815
Tuberculosis Outbreak in a Housing Unit for Human Immunodeficiency Virus—Infected Patients in a Correctional Facility: Transmission Risk Factors and Effective Outbreak Control

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In 1995, an outbreak of tuberculosis (TB) occurred among residents of a correctional-facility housing unit for inmates infected with human immunodeficiency virus (HIV). We isolated and treated patients who were suspected to have TB. To determine risk factors for in-prison transmission of TB, we conducted a case-control study to compare inmate case patients infected with a distinct outbreak strain of TB with control subjects who resided in the HIV unit. We identified 15 case patients during a 4-month period. Among inmates with a CD4 count of µ100 cells/mm3, case patients were more likely than control subjects to spend ≥20 hours per week in a communal day room (odds ratio, 42; P = .002) and were less likely to have a television in their single-person room (odds ratio, 0.10; P = .003). The communal day room was a likely site of transmission. Successful collaboration between the correctional system and public health departments halted the outbreak.

Journal Article.  5186 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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