Journal Article

Quantification of Adenovirus DNA in Plasma for Management of Infection in Stem Cell Graft Recipients

A. C. Lankester, M. J. D. van Tol, E. C. J. Claas, J. M. Vossen and A. C. M. Kroes

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 34, issue 6, pages 864-867
Published in print March 2002 | ISSN: 1058-4838
Published online March 2002 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/339073
Quantification of Adenovirus DNA in Plasma for Management of Infection in Stem Cell Graft Recipients

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We used a real-time polymerase chain reaction method for quantification of adenovirus to monitor the dynamics of viral DNA load in plasma in pediatric stem-cell graft recipients. Two cases are described to demonstrate that detection and quantification of the adenovirus DNA load at regular intervals may be important to document the stage of adenovirus infection, to make decisions on clinical intervention, and to accurately monitor the response to antiviral therapy.

Journal Article.  2372 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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