Journal Article

Assessment of the Binax NOW <i>Streptococcus pneumoniae</i> Urinary Antigen Test in Children with Nasopharyngeal Pneumococcal Carriaged

Davidson H. Hamer, Josefina Egas, Bertha Estrella, MacLeod William B., Griffiths Jeffrey K. and Fernando Sempértegui

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 34, issue 7, pages 1025-1028
Published in print April 2002 | ISSN: 1058-4838
Published online April 2002 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1086/339446
Assessment of the Binax NOW Streptococcus pneumoniae Urinary Antigen Test in Children with Nasopharyngeal Pneumococcal Carriaged

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We evaluated the Binax NOW Streptococcus pneumoniae urinary antigen assay by testing 210 healthy children aged 2–60 months living in urban slums of Quito, Ecuador. Healthy children with nasopharyngeal carriage of S. pneumoniae were significantly more likely to have positive urinary antigen test results than were children who were not carriers (30 of 138 vs. 3 of 71 children; χ2 = 10.8; P < .001). The rate of nasopharyngeal carriage of S. pneumoniae decreased with increasing age; the lowest rates were found in children with the worst nutritional status.

Journal Article.  2056 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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