Journal Article

Emergence of Multiple Drug-Resistant Human Cytomegalovirus Variants in 2 Patients with Human Immunodeficiency Virus Infection Unresponsive to Highly Active Antiretroviral Therapy

Fausto Baldanti, Stefania Paolucci, Aldo Parisi, Luca Meroni and Giuseppe Gerna

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 34, issue 8, pages 1146-1149
Published in print April 2002 | ISSN: 1058-4838
Published online April 2002 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/339750
Emergence of Multiple Drug-Resistant Human Cytomegalovirus Variants in 2 Patients with Human Immunodeficiency Virus Infection Unresponsive to Highly Active Antiretroviral Therapy

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In 2 patients infected with human immunodeficiency virus (HIV), highly active antiretroviral therapy was unable to suppress HIV replication as a result of the emergence of drug-resistant HIV variants. Human cytomegalovirus (HCMV) retinitis developed in both patients, and an unusually complex mixture of drug-resistant HCMV variants was detected in both patients.

Journal Article.  2195 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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