Journal Article

Epidemiology and Clinical Spectrum of Blastomycosis Diagnosed at Manitoba Hospitals

Tracy L. Crampton, R. Bruce Light, Greg M. Berg, Michael P. Meyers, Gary C. Schroeder, Earl S. Hershfield and John M. Embil

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 34, issue 10, pages 1310-1316
Published in print May 2002 | ISSN: 1058-4838
Published online May 2002 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/340049
Epidemiology and Clinical Spectrum of Blastomycosis Diagnosed at Manitoba Hospitals

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Blastomyces dermatitidis is a dimorphic fungus endemic to Canada and the United States. Few reports regarding blastomycosis in Canada have been published. We retrospectively reviewed the medical charts of 143 patients with confirmed cases of blastomycosis diagnosed in hospitals in Manitoba, Canada, from 1988 through 1999. The annual incidence rate of blastomycosis in Manitoba was 0.62 cases per 100,000 population, compared with 7.11 cases per 100,000 population in the Kenora, Ontario district. The average age of patients was 38.0 years, and males accounted for 65.0% of cases. An increased incidence of blastomycosis was observed in the Aboriginal subpopulation. Organ systems involved were as follows: respiratory system (93.0% of cases), skin (21.0%), bone (13.3%), genitourinary tract (1.4%), and the central nervous system (1.4%); 6.3% of patients died, and death was associated with a short clinical course. This study provides a summary of the current status of blastomycosis in this area of endemicity in Canada.

Journal Article.  4338 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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