Journal Article

The Promise of Novel Technology for the Prevention of Intravascular Device–Related Bloodstream Infection. II. Long-Term Devices

J. Crnich Christopher and Dennis G. Maki

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 34, issue 10, pages 1362-1368
Published in print May 2002 | ISSN: 1058-4838
Published online May 2002 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/340105
The Promise of Novel Technology for the Prevention of Intravascular Device–Related Bloodstream Infection. II. Long-Term Devices

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Intravascular devices (IVDs) are widely used for vascular access but are associated with a substantial risk of IVD-related bloodstream infection (BSI). The development of novel technologies based on our understanding of pathogenesis promises a quantum reduction in IVD-related infections in an era of growing nursing shortage. Infections of long-term IVDs (most are in place for ⩾10 days), including cuffed and tunneled central venous catheters (CVCs), implanted subcutaneous central venous ports, and peripherally inserted central catheters (PICCs), are primarily due to microorganisms that gain access to the catheter hub and lumen. Novel securement devices and antibiotic lock solutions have been shown to reduce the risk of IVD-related BSI in prospective randomized trials. The challenge for the future will be to identify new preventative technologies and to begin to more-widely adapt those technologies that have already been shown to be efficacious and cost effective.

Journal Article.  4876 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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