Journal Article

Virus Load during Primary Human Immunodeficiency Virus (HIV) Type 1 Infection Is Related to the Severity of Acute HIV Illness in Kenyan Women

Ludo Lavreys, Jared M. Baeten, Julie Overbaugh, Dana D. Panteleeff, Bhavna H. Chohan, Barbra A. Richardson, Kishorchandra Mandaliya, Jeckoniah O. Ndinya-Achola and Joan K. Kreiss

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 35, issue 1, pages 77-81
Published in print July 2002 | ISSN: 1058-4838
Published online July 2002 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/340862
Virus Load during Primary Human Immunodeficiency Virus (HIV) Type 1 Infection Is Related to the Severity of Acute HIV Illness in Kenyan Women

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We evaluated the association between the severity of primary human immunodeficiency virus type 1 (HIV-1) illness and HIV-1 plasma virus load before seroconversion using stored plasma samples obtained from 74 prostitutes in Mombasa, Kenya. Fever, vomiting, headache, fatigue, arthralgia, myalgia, sore throat, skin rash, or being too sick to work were each associated with significantly higher virus loads before HIV-1 seroconversion, and each additional symptom or sign was associated with an increase in virus load of 0.4 log10 copies/mL.

Journal Article.  2145 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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