Journal Article

An Outbreak of Varicella among Children Attending Preschool and Elementary School in Illinois

Mark S. Dworkin, Charles E. Jennings, Jayne Roth-Thomas, Jo Ellen Lang, Carol Stukenberg and John R. Lumpkin

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 35, issue 1, pages 102-104
Published in print July 2002 | ISSN: 1058-4838
Published online July 2002 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/340868
An Outbreak of Varicella among Children Attending Preschool and Elementary School in Illinois

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In our investigation of a varicella outbreak among students in preschool, kindergarten, and grades 1–3 in Winnebago County, Illinois, we found an overall varicella vaccine efficacy of 88%, evidence that the circulating virus was a wild-type strain (as determined by polymerase chain reaction analysis), and evidence that vaccination of children ⩽15 months of age was associated with an increased risk for breakthrough varicella (relative risk, 3.7; 95% confidence interval, 1.1–13.1; P = .04). The efficacy of varicella vaccine might be improved if administration of the initial vaccine dose is delayed until children are ⩾15 months of age.

Journal Article.  1953 words. 

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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