Journal Article

A Novel, Multiple Drug–Resistant, Serotype 24F Strain of <i>Streptococcus pneumoniae</i> That Caused Meningitis in Patients in Naples, Italy

Annalisa Pantosti, Giovanni Gherardi, Marco Conte, Francesco Faella, Giordano Dicuonzo and Bernard Beall

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 35, issue 2, pages 205-208
Published in print July 2002 | ISSN: 1058-4838
Published online July 2002 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/341250
A Novel, Multiple Drug–Resistant, Serotype 24F Strain of Streptococcus pneumoniae That Caused Meningitis in Patients in Naples, Italy

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Three adult patients in Naples, Italy, had meningitis due to multiple drug—resistant serotype 24F Streptococcus pneumoniae isolates. The 3 isolates were genetically indistinguishable and shared pbp2b and pspA sequence types with previously characterized penicillin-resistant clones. This serotype 24F strain was found to be the same clonal type as a previously characterized, penicillin-resistant serotype 14 strain. The novel strain has probably arisen through transformation of a serotype 14 strain with type 24F capsular biosynthetic operon sequences.

Journal Article.  2621 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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